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Instructor: Eugene Pinkhassik
Office: SM 405
Phone: (901) 678-4430
E-mail: epnkhssk@memphis.edu
Class Schedule: MW 4:00 – 5:25 SM 222
Prerequisite: General Organic Chemistry (3311 and 3312) or permission of instructor
Office Hours: almost anytime
Textbook: Supramolecular Chemistry by Steed and Atwood
Course description:
Supramolecular Chemistry is a rapidly developing field of research that involves the use of noncovalent interactions to assemble molecules into stable well-defined structures. This course will introduce students to the exciting field of Supramolecular Chemistry. The course will consist of lectures and laboratory practice.
The following topics will be covered:
Fundamentals of Supramolecular Chemistry
Types of noncovalent binding; Molecular Complexes; Complexation of Ions; Podands, Crown Ethers, Criptands, Calixarenes; Macrocyclic Effect; Complexation of Neutral Molecules; Self-Assembly
Supramolecular Chemistry and Biological Processes
Receptor-Substrate Interactions; Drug Binding; Protein Folding
Synthesis of Supramolecules
Synthesis of Macrocycles; Synthesis of Receptors for Cations, Anions, and Neutral Molecules; Non-Covalent Synthesis
Physical Methods in Supramolecular Chemistry
Spectroscopy in Supramolecular Chemistry; Determination of Stoichiometry, Stability Constants, and Geometry of Complexes;
Application of Supramolecular Chemistry
Supramolecular Catalysis; Membrane Transport; Sensors; Phase-Transfer Catalysis; Supramolecular Devices and Switches; Molecular Materials
