UM Chemistry/Graduate/Graduate Courses/CHEM 4311/6311

This course is recommended for chemistry and related majors seeking more in-depth study of organic chemistry.

Course Description: Further study of physical organic chemistry, spectrometric methods of identification of organic compounds, and modern organic synthesis.
Three lecture hours per week; 3 credit hours.

Prerequisite: Satisfactory completion of a one year course in organic chemistry, equivalent to CHEM 3311 and CHEM 3312.

Textbook and other materials:
A general organic chemistry textbook (Bruice, P. Y., Organic Chemistry, for example) is recommended.
Three textbooks are required:

• Sykes, P., A Guidebook to Mechanism in Organic Chemistry, 7th ed.
• Silverstein, R. M.; Webster, F. X., Kiemle, D. J. Spectrometric Identification of Organic Compounds, 7th ed.
• Warren, S. G., Organic Synthesis: The Disconnection Approach.

Course Objectives:
Review of general organic chemistry; more advanced treatment of structure and mechanism; application of modern techniques in NMR spectroscopy to structure determination; introduction to design and planning of synthesis of organic compounds.

Grades:
Three examinations and assignments will be given during the semester. A comprehensive final examination will be administered in class at the assigned time. Each test and the sum of the assignments will count 20% toward the grade for the course. Grades are expected to be in the range: A > 80 > B > 65 > C > 50 > D

Policies:

• Within certain restrictions, books and journals may be used to help with take-home tests but not the Internet, and assistance may not be sought from other students or faculty.
• Tardiness and unexcused absence from class are unprofessional behaviors which should be avoided, but attendance will not be graded.
• Electronic devices such as cell phones and pagers should be turned off in the classroom.
• Reasonable and appropriate accommodations will be made for students who present a memo from Student Disability Services.

Academic Integrity and Student Conduct: Expectations for academic integrity and student conduct are described in detail on the website of the Office of Student Judicial and Ethical Affairs(http://saweb.memphis.edu/judicialaffairs). Please take a look, in particular, at the sections about “Academic Dishonesty,” “Student Code of Conduct and Responsibilities,” and “Disruptive Behaviors.” I will expect students to be aware of these guidelines and to conduct themselves accordingly.

Reasonable and appropriate accommodations will be provided to students with disabilities who present a memo from Student Disability Services (SDS).  

Course Schedule updated 10 September 2009

Assignment of Problem Sets updated 10 September 2009

Problem Sets and Answers

Sykes CH1-2 problems Structure-Reactivity-Energetics

Sykes CH1-2 answers  updated 29 September 2009

Sykes CH3-8 problems Acid/Base Chemistry-Carbonyl Addition

Sykes CH3-8 answers updated 14 October 2009

Sykes CH10 Problems Carbanion Chemistry

Sykes CH10 answers updated 18 October 2009

Sykes CH13 Problems Linear Free Energy Relationships

Sykes CH13 answers updated 19 October 2009

Warren CH1-6 Problems Synthesis

Warren CH7-11 Problems Synthesis

Warren CH13,17,19,21 Problems Synthesis

Warren CH23-25 Problems Synthesis

Course Notes:

Sykes CH 1 Electronic Structure updated 8 September 2009

Sykes CH 2 Energetic and Kinetics updated 10 September 2009

Electron Flow

Sykes CH3 Acid Base Chemistry updated 24 September 2009

pKa Table

Sykes CH 8 CO Addition updated 24 September 2009

Sykes CH10 Carbanions updated 24 September 2009

Sykes CH13 Linear Free Energy Relationships

Sample Physical Organic Exam

Mass Spectroscopy

Infrared Spectroscopy

Proton NMR Spectroscopy

Dynamic NMR example

Carbon and 2D  NMR Spectroscopy

Warren CH1-6 Synthesis

Warren CH7-11 Synthesis

Warren CH13,17,19,21 Synthesis

Warren CH23-25 Synthesis

Warren CH26-29 Synthesis

Succeeding in 4311-6311