Alternative worked solutions to problem 14 in section 2.4.
Handouts
Examinations
Preparation Test (1/18/2005)
Midterm Examination I followup (due 3/29/2005)
Midterm Examination II followup (due 5/3/2005)
Lecture Notes
First Topic (1/18/2005) - Historical Development of Medicinal Chemistry
Second Topic (1/20/2005-1/27/2005) - Overview of Drug Targets (Handouts)
Third Topic (1/29/2005) - Malaria (Handouts)
Fourth Topic (2/1/2005 & 2/8/2005) - Overview of Computers in Drug Design (Handouts)
Fifth Topic (2/8/2005 - 2/10/2005) - Receptor Pharmacology (Handouts)
Sixth Topic (2/15/2005-2/17/2005) - Pharmacophore Modeling (Handouts)
Seventh Topic (2/17/2005-2/24/2005) - QSAR Modeling (Handouts)
Eighth Topic (2/24/2005-3/1/2005) - Docking (Handouts)
Ninth Topic (3/15/2005) - Structural Modification (Handouts)
Tenth Topic (3/22/2005-3/24/2005) - Enzymes (Handouts)
Eleventh Topic (3/29/2005-3/31/2005) - Enzyme Inhibition (Handouts)
Twelfth Topic (4/5/2005-4/7/2005) - Synthetic Planning
Thirteenth Topic (4/7/2005) - Combinatorial Synthesis
Fourteenth Topic (4/12/2005-4/14/2005) - Drug Metabolism (Handouts, In-class problem solution)
Fifteenth Topic (4/19/2005) - Prodrugs (Handouts)
Sixteenth Topic (4/26/2005) - Stereochemical Considerations (Handouts)
CHEM6315 Presentation
James Fells - QSAR in Development of Antidepressants
Links to Useful Resources
Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB): Enzyme nomenclature
Chemical Information Services at the National Cancer Institute
Sigma-Aldrich Catalog - an extensive source of commercially available chemical reagents
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purposes. Questions, problems, and errors should be sent to aparrill@memphis.edu.