CHEM 3312
Organic Chemistry 2
Spring 2008, Section 001: MWF 9:10 - 10:05 am
The sections of the textbook that cover the material for each lecture are included in the list below, but note that the correspondence between the lectures and the textbook will not be perfect. If you have time to read the material before the lecture, you are encouraged to do so, but you should certainly read the material after the lecture and supplement your lecture notes as you read. We will also frequently refer to material from CHEM 3311, so be prepared to re-read material from Chapters 1 - 12.
Homework assignments are problems from the ends of each chapter. Answers should be written out and brought to the next class period. Note that assignments are the minimum number of problems that it is necessary to work to feel comfortable with proficiency. You are encouraged to work as many more problems as you have time for.
It is a nuisance that knowledge can only be acquired by hard work. W.
Somerset Maugham
Schedule
| Class date | Reading | Topics and Problems |
| Jan 14 | Chapter 13 | NMR Spectroscopy - slides |
| Jan 16 | 13:19 - 20 | Carbon-13 NMR continued Problems: 13.52, 53, 59, 73 |
| Jan 18 | 13:7-13 | Proton NMR - slides Browse the online database (AIST SDBS) for examples Problems: 13.43, 44, 45, 46, 50, 56, 71, 72 |
| Jan 23 | Proton NMR continued WORK THE PROBLEMS! |
|
| Jan 25 | Chapter 14 14: 1 - 8 |
Aromaticity; nomenclature of benzene derivatives Problems: 14.30, 31 |
| Jan 28 | 14: 9 - 15 | Electrophilic Aromatic Substitution (EAR) Problems: 14.32, 41, 42 |
| Jan 30 | Chapter 15 15: 1 - 3 |
EAR in Substituted Benzenes Problems: 15.34, 35, 38, 44, 45 Help session today, 4 pm room 304 (spectroscopy + ...) |
| Feb 1 | 14: 16 - 19 15: 4 - 6 |
Common Reactions of Substituents; Synthesis 1 Problems: 14.35, 45; 15.42 (a,b,c,e,g), 52, 54, 55, 57 |
| Feb 4 | 15: 7 - 8 | Synthesis of Benzene Derivatives Problems: 15.43, 48, 55 |
| Feb 6 | 15: 9 -11 | Chemistry of Diazonium Salts Problems: 15.42 (d,f,h), 49, 67 |
| Feb 8 | 15: 12 - 13 | Nucleophilic Aromatic Substitution Problems: 15.58, 59, 70 Help session today, 1 pm room 222 |
| Feb 11 | ||
| Feb 13 | Practice test | TEST 1: Chapters 13 - 15 |
| Feb 15 | 16: 1-4 | Carboxylic Acid Derivatives; Nomenclature and Properties Problems: 16.45, 46; 1.89, 95 |
| Feb 18 | 16: 5 - 10 | Nucleophilic Acyl Substitution Problems: 16.47, 52, 58a, 61 |
| Feb 20 | 16: 11 - 17 | Acid Catalysis Problems: 16.53, 56, 57, 58b, 79 |
| Feb 22 | 16: 18 - 23 | Synthesis Problems: 16.49, 54, 63, 64, 67, 75, 81 |
| Feb 25 | 17: 1 - 5 | Aldehydes and Ketones Problems: 17.45, 47, 57, 61, 65a, 78 |
| Feb 27 | 17: 6 - 7 | Reduction of Carbonyl Compounds Problems: 17.46d,f, 48, 53f, 59 |
| Feb 29 | 17: 8 - 11 | Addition-Elimination Reactions Problems: 17.46, 49, 50, 53, 56, 64 |
| Mar 3 - 7 | Spring Break | |
| Mar 10 | 18: 1 - 7 | Halogenation of Carbonyl Compounds Problems: 18.52, 56, 61 |
| Mar 12 | 18: 12 - 14 | Aldol and Related Condensations Problems: 18.53, 57, 58, 65b |
| Mar 14 | 18: 15 - 18 | Claisen and Related Condensations Problems: 18.50, 79 |
| Mar 17 | 18: 8 - 11, 19, 20 | Enolate Alkylation and Conjugate Addition Problems: 18.49, 59, 62, 81, 82 |
| Mar 19 | Synthesis Problems: 18.55, 60, 68, 84, 85 |
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| Mar 21 | Practice Test | TEST 2: Chapters 16 - 18 |
| Mar 24 | 19: 1 - 9 | Oxidation of ketones and alkenes Problems: 19.30, 31, 34, 37, 42 |
| Mar 26 | Chapter 21 21: 1 - 4 |
Carbohydrates |
| Mar 28 | 21: 5 - 10 | Carbohydrates Problems: 30, 31, 35, 47 |
| Mar 31 | 21: 11 - 17 | Hemiacetals and Glycosides Problems: 51, 52, 53 |
| Apr 2 | 25: 1 - 5, 7 | Glycolysis, ATP, and NAD+ Problems: 25.24, |
| Apr 4 | 24: 1 - 3 25: 6 |
Fatty Acid Metabolism Problems: 25.31, |
| Apr 7 | 24: 4 25: 10 |
Citric Acid Cycle Problems: 25.27, |
| Apr 9 | 22: 1 - 7 | Amino-acids Problems: 22.44, 47, 53 |
| Apr 11 | 22: 8 - 13 | Primary Structure and Sequencing Problems: 22.45, 66 |
| Apr 14 | 22: 14 - 16 | Three-Dimensional Structure (tutorial) Problems: |
| Apr 16 | 27: 1 - 9 | Nucleic Acids Problems: 21, 27, 30, |
| Apr 18 | 27: 10 - 13 | Sequencing and Synthesis Problems: |
| Apr 21 | Practice Test | TEST 3 |
| Apr 23 | Practice Test Answers |
Review |
| Apr 25 | 10:30 am - 12:30 | FINAL EXAMINATION |
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